Anapolon (Oxymetholone)

Oxymetholone is an anaboic steroid that has been used in the treatment of anaemias such as aplastic anaemia. It is also used in veterinary medicine and given to small, older animals to improve their appetitie and increase strength and vitality. Oxymetholone is commonly administered orally. Another brand name for it is Anapolon.

The ratio of anabolic to androgenic functions is known as The Therapeutic Index. The therapeutic index was developed in an attempt to classify the anabolic and androgenic effects of anabolic steroids. The reference point for the index is testosterone, which is assigned a therapeutic index of 1. Anabolic steroids would generally have a therapeutic index of greater than 1 since they tend to magnify the anabolic functions and reduce the androgenic functions.
 

Therapeutic Index for Select Anabolic Steroids

Trade Name     Drug/Chemical Name            Original Manufacturer   Therapeutic Index

Testoderm         Testosterone                   Alza                                                    1
Androderm        Testosterone                   Smith-Kline                                      1
Anapolon           Oxymetholone                 Park-Davis                                      3-8

Anabolic steroids exploit the difference in actions through estrogen metabolites, 5?-reduced metabolites, and direct testosterone binding on fat and brain, reproductive tissues, and skeletal muscle. Nitrogen balance provides an approximate index of muscle protein status, while changes in body weight provide another measure of anabolism. When these effects were compared between orally active anabolic steroids, Oxymetholone was three (3) times more potent than testosterone in producing a positive nitrogen balance and weight gain in adults. Anapolon 50

Anabolic properties that are advantageous to an athlete are likely to extend beyond the effects of nitrogen retention and weight gain. Other typical anabolic properties range from increasing bone mineral content, counteracting the effect of corticosteroids to break down tissue, behavior related to motivation and extraversion, or simply increasing appetite. Anapolon may affect each of these points differently.

According to various athlete surveys, Oxymetholone is one of the most popular of the 17-alkylated anabolic steroids and this includes its use in Olympic contestants testing positive for steroids. Most athletes set their doses based on what seems to work for ther friends since there is no established dose for strength or weight gain for any anabolic steroid. Anapolon is used at very high doses, typically 150 mg/day in conjunction with other anabolic steroids. Oxymetholone's chemical formula is C21H32O3.

Brand Names for Oxymetholone

Hemogenin (Brazil); Androyd (India); Androlic (Thailand); Anapolon (Turkey); Oxymetholone (USA).
 

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